SFRS12 antibody (N-Term)

Catalog No. ABIN2784667

Cited in 1 publication. The Rabbit Polyclonal anti-SFRS12 antibody (ABIN2784667) specifically detects SFRS12 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Rabbit, Dog and Zebrafish (Danio rerio) samples.

Quick Overview for SFRS12 antibody (N-Term) (ABIN2784667)

Target: SFRS12 (SREK1) (Splicing Regulatory Glutamine/lysine-Rich Protein 1 (SREK1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SFRS12 Antibody

Binding Specificity: N-Term

Purpose: SFRS12 Antibody - N-terminal region

Sequence: DPSSVGVAQH LTNTVFIDRA LIVVPCAEGK IPEESKALSL LAPAPTMTSL

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SFRS12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51872-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SFRS12 antibody (ABIN2784667)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for SFRS12

Target: SFRS12 (SREK1) (Splicing Regulatory Glutamine/lysine-Rich Protein 1 (SREK1))

Alternative Name: SFRS12

Background:

Background Information: SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins.SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002 [PubMed 11991645]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-78 AW963850.1 1-78 79-415 AK091758.1 1-337 416-2238 BC067770.1 609-2431 2239-3654 BC112343.1 1800-3215 3655-3660 AK125893.1 3379-3384 3661-4030 AL049309.1 705-1074

Gene Name: Splicing regulatory glutamine/lysine-rich protein 1

Alternative Symbols: SFRS12, SRrp86, SRrp508

Protein Name: Splicing regulatory glutamine/lysine-rich protein 1

Molecular Weight: 72kDa

Gene ID: 140890

NCBI Accession: NP_001070667

UniProt: Q8WXA9