SLC47A2 antibody (C-Term)

Catalog No. ABIN2784682

Cited in 1 publication. The Rabbit Polyclonal anti-SLC47A2 antibody (ABIN2784682) specifically detects SLC47A2 in WB. The antibody is reactive with Human, Dog and Horse samples.

Quick Overview for SLC47A2 antibody (C-Term) (ABIN2784682)

Target: SLC47A2 (Solute Carrier Family 47, Member 2 (SLC47A2))

Reactivity: Human, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC47A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC47A2 Antibody

Binding Specificity: C-Term

Purpose: SLC47A2 Antibody - C-terminal region

Sequence: TYSRSECHVD FFRTPEEAHA LSAPTSRLSV KQLVIRRGAA LGAASATLMV

Predicted Reactivity: Dog: 85%, Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC47A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC47A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51904-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC47A2 antibody (ABIN2784682)

Tanihara, Masuda, Sato, Katsura, Ogawa, Inui: "Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters." in: Biochemical pharmacology, Vol. 74, Issue 2, pp. 359-71, (2007) (PubMed).

Target Details for SLC47A2

Target: SLC47A2 (Solute Carrier Family 47, Member 2 (SLC47A2))

Alternative Name: SLC47A2

Background:

Background Information: SLC47A2 is a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance.This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene Name: Solute carrier family 47, member 2

Alternative Symbols: MATE2, MATE2K, MATE2-B, MATE2-K

Protein Name: Multidrug and toxin extrusion protein 2

Molecular Weight: 65 kDa

Gene ID: 146802

NCBI Accession: NP_001093116

UniProt: Q86VL8