AP3S1 antibody (N-Term)

Catalog No. ABIN2784696

This Rabbit Polyclonal antibody specifically detects AP3S1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for AP3S1 antibody (N-Term) (ABIN2784696)

Target: AP3S1 (Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3S1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AP3S1 Antibody

Binding Specificity: N-Term

Purpose: AP3S1 Antibody - N-terminal region

Sequence: IKAILIFNNH GKPRLSKFYQ PYSEDTQQQI IRETFHLVSK RDENVCNFLE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AP3S1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AP3S1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51935-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP3S1

Target: AP3S1 (Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))

Alternative Name: AP3S1

Background:

Targeted Subunit: sigma-1

Background Information: AP3S1 is part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

Gene Name: Adaptor-related protein complex 3, sigma 1 subunit

Alternative Symbols: CLAPS3, Sigma3A

Protein Name: AP-3 complex subunit sigma-1

Molecular Weight: 22kDa

Gene ID: 1176

NCBI Accession: NP_001275

UniProt: Q92572