DPYSL2 antibody (Middle Region)
Quick Overview for DPYSL2 antibody (Middle Region) (ABIN2784711)
Target
See all DPYSL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- NIFEGMECRG SPLVVISQGK IVLEDGTLHV TEGSGRYIPR KPFPDFVYKR
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Characteristics
- This is a rabbit polyclonal antibody against DPYSL2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DPYSL2
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 572 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
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Alternative Name
- DPYSL2
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Background
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DPYSL2 belongs to the DHOase family. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. The protein plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Alias Symbols: CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP2, CRMP-2, ULIP-2
Protein Interaction Partner: DPYSL5, GORASP2, UBC, DPYSL3, DPYSL2, CRMP1, PUS7, RANBP6, XPO7, HSPH1, EIF3J, PDE3A, DNAJB1, LEF1, IQCB1, TUBB, TUBA1A, Htt, CDK2, SIRT7, ELAVL1, DISC1, TNIK, DPYSL4, GSK3B, NUMB, PLD2, ROCK1, RHOA, AP2A1,
Protein Size: 572 -
Molecular Weight
- 62 kDa
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Gene ID
- 1808
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NCBI Accession
- NM_001386, NP_001377
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UniProt
- Q16555
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Pathways
- Regulation of Cell Size
Target
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