CHN1 antibody (Middle Region)

Catalog No. ABIN2784718

This Rabbit Polyclonal antibody specifically detects CHN1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit and Saccharomyces cerevisiae.

Quick Overview for CHN1 antibody (Middle Region) (ABIN2784718)

Target: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHN1 Antibody

Binding Specificity: Middle Region

Sequence: KVYSCDLTTL VKAHTTKRPM VVDMCIREIE SRGLNSEGLY RVSGFSDLIE

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 77%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CHN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 459 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHN1

Target: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Alternative Name: CHN1

Background: CHN1 contains 1 phorbol-ester/DAG-type zinc finger, 1 Rho-GAP domain and 1 SH2 domain. CHN1 is a GTPase-activating protein for p21-rac and a phorbol ester receptor. It may play an important role in neuronal signal-transduction mechanisms.
Alias Symbols: ARHGAP2, CHN, RHOGAP2, NC, DURS2
Protein Interaction Partner: HEMK1, NCK2, Grin2a, ERBB2, nef, MAPK8IP2, GTF3C1, CDK5R1, BMPR1B, RAC1, TGFBR1, RPS3A, CDK5, ACVR1,
Protein Size: 459

Molecular Weight: 53 kDa

Gene ID: 1123

NCBI Accession: NM_001822, NP_001813

UniProt: P15882