CHN1 antibody (C-Term)

Catalog No. ABIN2784719

Product Details anti-CHN1 Antibody

Target: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LITYDAYPKF IESAKIMDPD EQLETLHEAL KLLPPAHCET LRYLMAHLKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CHN1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHN1

Target: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Alternative Name: CHN1 (ARHGAP2 Products)

Background: This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ARHGAP2, CHN, DURS2, RHOGAP2, NC
Protein Interaction Partner: HEMK1, NCK2, Grin2a, ERBB2, nef, MAPK8IP2, GTF3C1, CDK5R1, BMPR1B, RAC1, TGFBR1, RPS3A, CDK5, ACVR1,
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 1123

NCBI Accession: NM_001206602, NP_001193531