CHN1 antibody (C-Term)

Catalog No. ABIN2784719

The Rabbit Polyclonal anti-CHN1 antibody (ABIN2784719) specifically detects CHN1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig and Rabbit samples.

Quick Overview for CHN1 antibody (C-Term) (ABIN2784719)

Target: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Zebrafish (Danio rerio), Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHN1 Antibody

Binding Specificity: C-Term

Sequence: LITYDAYPKF IESAKIMDPD EQLETLHEAL KLLPPAHCET LRYLMAHLKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CHN1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 334 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHN1

Target: CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))

Alternative Name: CHN1

Background: This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ARHGAP2, CHN, DURS2, RHOGAP2, NC
Protein Interaction Partner: HEMK1, NCK2, Grin2a, ERBB2, nef, MAPK8IP2, GTF3C1, CDK5R1, BMPR1B, RAC1, TGFBR1, RPS3A, CDK5, ACVR1,
Protein Size: 334

Molecular Weight: 36 kDa

Gene ID: 1123

NCBI Accession: NM_001206602, NP_001193531