CSNK2A1/CK II alpha antibody (Middle Region)

Catalog No. ABIN2784725

This anti-CSNK2A1/CK II alpha antibody is a Rabbit Polyclonal antibody detecting CSNK2A1/CK II alpha in WB. Suitable for Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for CSNK2A1/CK II alpha antibody (Middle Region) (ABIN2784725)

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK2A1/CK II alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSNK2A1/CK II alpha Antibody

Binding Specificity: Middle Region

Sequence: LGCMLASMIF RKEPFFHGHD NYDQLVRIAK VLGTEDLYDY IDKYNIELDP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CSNK2A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CSNK2A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 391 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Alternative Name: CSNK2A1

Background: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. CSNK2A1 represents the alpha subunit.Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.
Alias Symbols: CK2A1, CKII, CKII alpha
Protein Interaction Partner: MAGEA11, HDAC3, RNF111, NFYA, SGT1, STAC3, SUGT1, THAP1, AKT1, AURKA, CEP76, TP53, CEP57, RPS3, EGFR, UBC, POP1, WWOX, RNF2, rev, NAP1, EPB41L2, CALD1, HECW2, CDK11A, CAV2, CSNK2B, RNF11, NRF1, MYH9, IGSF8, ICAM1, HMGA1, HDAC1, GCH1, ACE, CSNK2A2, PRNP, D
Protein Size: 391

Molecular Weight: 45 kDa

Gene ID: 1457

NCBI Accession: NM_001895, NP_001886

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interactome