DNM2 antibody (N-Term)

Catalog No. ABIN2784752

The Rabbit Polyclonal anti-DNM2 antibody has been validated for WB. It is suitable to detect DNM2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for DNM2 antibody (N-Term) (ABIN2784752)

Target: DNM2 (Dynamin 2 (DNM2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNM2 Antibody

Binding Specificity: N-Term

Sequence: FLHCKSKKFT DFDEVRQEIE AETDRVTGTN KGISPVPINL RVYSPHVLNL

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Dnm2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Dnm2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 870 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNM2

Target: DNM2 (Dynamin 2 (DNM2))

Alternative Name: Dnm2

Background: Dnm2 is involved in the formation of clathrin-coated vesicles, It plays a role in receptor mediated endocytosis including endocytosis of AT1A angiotensin receptors.
Alias Symbols: DYIIAAB
Protein Interaction Partner: Sorbs1, Ap2a1, Sorbs2, DYNLL1, Vav1, Cav1, Shank1, Shank2, Cttn, Dyrk1a,
Protein Size: 870

Molecular Weight: 95 kDa

Gene ID: 25751

NCBI Accession: NM_013199, NP_037331

UniProt: P39052

Pathways: Toll-Like Receptors Cascades