DNM2 antibody (AA 520-744)

Catalog No. ABIN5611153

Product Details anti-DNM2 Antibody

Target: DNM2 (Dynamin 2 (DNM2))

Binding Specificity: AA 520-744

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DNM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human Dynamin-2 (AA: 520-744) expressed in E. coli.

Clone: 3F5F3

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10000, WB: 1:250 - 1:1000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for DNM2

Target: DNM2 (Dynamin 2 (DNM2))

Alternative Name: Dynamin-2 (DNM2 Products)

Background:

Description: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Aliases: DNM2,DYN2, CMT2M, DYNII, LCCS5, CMTDI1, CMTDIB, DI-CMTB

Molecular Weight: 98 kDa

Gene ID: 1785

HGNC: 1785

Pathways: Toll-Like Receptors Cascades