CST8 antibody (Middle Region)

Catalog No. ABIN2784761

This anti-CST8 antibody is a Rabbit Polyclonal antibody detecting CST8 in WB. Suitable for Human, Mouse, Rat, Horse, Rabbit, Dog, Cow and Pig.

Quick Overview for CST8 antibody (Middle Region) (ABIN2784761)

Target: CST8 (Cystatin 8 (CST8))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CST8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CST8 Antibody

Binding Specificity: Middle Region

Sequence: LKPVNASNAN VKQCLWFAMQ EYNKESEDKY VFLVVKTLQA QLQVTNLLEY

Predicted Reactivity: Cow: 90%, Dog: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CST8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CST8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 142 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CST8

Target: CST8 (Cystatin 8 (CST8))

Alternative Name: CST8

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing identified in mouse is suggested in human based on EST evidence but the full-length nature of putative variants has not been determined.
Alias Symbols: CRES
Protein Size: 142

Molecular Weight: 14 kDa

Gene ID: 10047

NCBI Accession: NM_005492, NP_005483

UniProt: O60676