CST8 antibody (N-Term)

Catalog No. ABIN2787973

Product Details anti-CST8 Antibody

Target: CST8 (Cystatin 8 (CST8))

Binding Specificity: N-Term

Reactivity: Human, Rat, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CST8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLEYLIDVEI ARSDCRKPLS TNEICAIQEN SKLKRKLSCS FLVGALPWNG

Predicted Reactivity: Dog: 90%, Horse: 85%, Human: 100%, Rabbit: 83%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CST8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CST8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 142 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CST8

Target: CST8 (Cystatin 8 (CST8))

Alternative Name: CST8 (CST8 Products)

Synonyms: CRES antibody, CTES5 antibody, Cres antibody, Cst-rs1 antibody, cystatin 8 antibody, cystatin 8 (cystatin-related epididymal spermatogenic) antibody, CST8 antibody, Cst8 antibody

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing identified in mouse is suggested in human based on EST evidence but the full-length nature of putative variants has not been determined.
Alias Symbols: CRES
Protein Size: 142

Molecular Weight: 14 kDa

Gene ID: 10047

NCBI Accession: NM_005492, NP_005483

UniProt: O60676