Sec23 Homolog B antibody (Middle Region)

Catalog No. ABIN2784805

The Rabbit Polyclonal anti-Sec23 Homolog B antibody is suitable to detect Sec23 Homolog B in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for Sec23 Homolog B antibody (Middle Region) (ABIN2784805)

Target: Sec23 Homolog B (SEC23B)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sec23 Homolog B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sec23 Homolog B Antibody

Binding Specificity: Middle Region

Purpose: SEC23B Antibody - middle region

Sequence: SFSLYPQFMF HLRRSPFLQV FNNSPDESSY YRHHFARQDL TQSLIMIQPI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC23B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEC23B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52162-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sec23 Homolog B

Target: Sec23 Homolog B (SEC23B)

Alternative Name: SEC23B

Background:

Background Information: SEC23B is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. SEC23B has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function SEC23B has been implicated in cargo selection and concentration.The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: Sec23 homolog B (S. cerevisiae)

Alternative Symbols: CWS7, CDAII, CDAN2, CDA-II, HEMPAS, hSec23B

Protein Name: Protein transport protein Sec23B

Molecular Weight: 86kDa

Gene ID: 10483

NCBI Accession: NP_006354

UniProt: Q15437