CHP antibody (N-Term)

Catalog No. ABIN2784874

This Rabbit Polyclonal antibody specifically detects CHP in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CHP antibody (N-Term) (ABIN2784874)

Target: CHP (Calcium Binding Protein P22 (CHP))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHP Antibody

Binding Specificity: N-Term

Purpose: CHP Antibody - N-terminal region

Sequence: FTSLDKGENG TLSREDFQRI PELAINPLGD RIINAFFPEG EDQVNFRGFM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CHP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52307-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHP

Target: CHP (Calcium Binding Protein P22 (CHP))

Alternative Name: CHP

Background:

Background Information: This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.

Gene Name: Calcium binding protein P22

Alternative Symbols: CHP, p22, p24, SPAX9, Sid470p, SLC9A1BP

Protein Name: Calcineurin B homologous protein 1

Molecular Weight: 22kDa

Gene ID: 11261

NCBI Accession: NP_009167

UniProt: Q99653

Pathways: Proton Transport, Regulation of Carbohydrate Metabolic Process, VEGF Signaling