MGLL antibody (N-Term)

Catalog No. ABIN2784881

The Rabbit Polyclonal anti-MGLL antibody is suitable to detect MGLL in samples from Human, Rat, Mouse, Dog, Pig and Rabbit. It has been validated for WB.

Quick Overview for MGLL antibody (N-Term) (ABIN2784881)

Target: MGLL (Monoglyceride Lipase (MGLL))

Reactivity: Human, Rat, Mouse, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGLL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MGLL Antibody

Binding Specificity: N-Term

Purpose: MGLL Antibody - N-terminal region

Sequence: METGPEDPSS MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT

Predicted Reactivity: Dog: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MGLL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MGLL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52321-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MGLL

Target: MGLL (Monoglyceride Lipase (MGLL))

Alternative Name: MGLL

Background:

Background Information: Monoglyceride lipase (MGLL, EC 3.1.1.23) functions together with hormone-sensitive lipase (LIPE, MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL, MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]).

Gene Name: Monoglyceride lipase

Alternative Symbols: MGL, HUK5, MAGL, HU-K5

Protein Name: Monoglyceride lipase

Molecular Weight: 34kDa

Gene ID: 11343

NCBI Accession: NP_009214

UniProt: Q6IBG9

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Lipid Metabolism