MGLL antibody (Middle Region)

Catalog No. ABIN2784882

The Rabbit Polyclonal anti-MGLL antibody is suitable to detect MGLL in samples from Human, Rat, Mouse, Dog, Pig, Rabbit, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for MGLL antibody (Middle Region) (ABIN2784882)

Target: MGLL (Monoglyceride Lipase (MGLL))

Reactivity: Human, Rat, Mouse, Dog, Pig, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGLL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MGLL Antibody

Binding Specificity: Middle Region

Sequence: PKALIFVSHG AGEHCGRYDE LAQMLKRLDM LVFAHDHVGH GQSEGERMVV

Predicted Reactivity: Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against Mgll. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of RAT Mgll

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MGLL

Target: MGLL (Monoglyceride Lipase (MGLL))

Alternative Name: Mgll

Background: Mgll converts monoacylglycerides to free fatty acids and glycerol. Mgll hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. It regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
Alias Symbols: MAGL
Protein Size: 303

Molecular Weight: 33 kDa

Gene ID: 29254

NCBI Accession: NM_138502, NP_612511

UniProt: Q8R431

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Lipid Metabolism