GABARAPL2 antibody (N-Term)

Catalog No. ABIN406207

This Rabbit Polyclonal antibody specifically detects GABARAPL2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit and Goat.

Quick Overview for GABARAPL2 antibody (N-Term) (ABIN406207)

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABARAPL2 Antibody

Binding Specificity: N-Term

Purpose: GABARAPL2 Antibody - N-terminal region

Sequence: KWMFKEDHSL EHRCVESAKI RAKYPDRVPV IVEKVSGSQI VDIDKRKYLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against GABARAPL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABARAPL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52325-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Alternative Name: GABARAPL2

Background:

Background Information: GABARAPL2 belongs to the MAP1 LC3 family. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. The protein first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.

Gene Name: GABA(A) receptor-associated protein-like 2

Alternative Symbols: ATG8, GEF2, ATG8C, GEF-2, GATE16, GATE-16

Protein Name: Gamma-aminobutyric acid receptor-associated protein-like 2

Molecular Weight: 14kDa

Gene ID: 11345

NCBI Accession: NP_009216

UniProt: P60520

Pathways: Autophagy