ALDH1L1 antibody (Middle Region)

Catalog No. ABIN2784888

The Rabbit Polyclonal anti-ALDH1L1 antibody (ABIN2784888) specifically detects ALDH1L1 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for ALDH1L1 antibody (Middle Region) (ABIN2784888)

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH1L1 Antibody

Binding Specificity: Middle Region

Purpose: ALDH1L1 Antibody - middle region

Sequence: LTLKAGIPKG VVNVLPGSGS LVGQRLSDHP DVRKIGFTGS TEVGKHIMKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Sheep: 100%, Yeast: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ALDH1L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH1L1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094369

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH1L1

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Alternative Name: ALDH1L1

Background:

Background Information: ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.

Gene Name: Aldehyde dehydrogenase 1 family, member L1

Alternative Symbols: FDH, FTHFD, 10-fTHF, 10-FTHFDH

Protein Name: Cytosolic 10-formyltetrahydrofolate dehydrogenase

Molecular Weight: 99kDa

Gene ID: 10840

NCBI Accession: NP_036322

UniProt: O75891