Keratin 24 antibody (Middle Region)

Catalog No. ABIN2784906

The Rabbit Polyclonal anti-Keratin 24 antibody is suitable to detect Keratin 24 in samples from Human, Horse and Pig. It has been validated for WB.

Quick Overview for Keratin 24 antibody (Middle Region) (ABIN2784906)

Target: Keratin 24 (KRT24)

Reactivity: Human, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 24 Antibody

Binding Specificity: Middle Region

Purpose: KRT24 Antibody - middle region

Sequence: GSVNMGSRDL VSGDSRSGSC SGQGRDSSKT RVTKTIVEEL VDGKVVSSQV

Predicted Reactivity: Horse: 93%, Human: 100%, Pig: 87%

Characteristics: This is a rabbit polyclonal antibody against KRT24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KRT24

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52386-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 24

Target: Keratin 24 (KRT24)

Alternative Name: KRT24

Background:

Background Information: KRT24 is a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.

Gene Name: Keratin 24

Alternative Symbols: K24, KA24

Protein Name: Keratin, type I cytoskeletal 24

Molecular Weight: 55kDa

Gene ID: 192666

NCBI Accession: NP_061889

UniProt: Q2M2I5