KLHDC3 antibody (N-Term)

Catalog No. ABIN2784950

The Rabbit Polyclonal anti-KLHDC3 antibody (ABIN2784950) specifically detects KLHDC3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for KLHDC3 antibody (N-Term) (ABIN2784950)

Target: KLHDC3 (Kelch Domain Containing 3 (KLHDC3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHDC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLHDC3 Antibody

Binding Specificity: N-Term

Purpose: KLHDC3 Antibody - N-terminal region

Sequence: MLRWTVHLEG GPRRVNHAAV AVGHRVYSFG GYCSGEDYET LRQIDVHIFN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against KLHDC3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLHDC3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52492-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLHDC3

Target: KLHDC3 (Kelch Domain Containing 3 (KLHDC3))

Alternative Name: KLHDC3

Background:

Background Information: The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination.

Gene Name: Kelch domain containing 3

Alternative Symbols: PEAS, dJ20C7.3

Protein Name: Kelch domain-containing protein 3

Molecular Weight: 43kDa

Gene ID: 116138

NCBI Accession: NP_476502

UniProt: Q9BQ90

Pathways: Chromatin Binding, ER-Nucleus Signaling