ASB17 antibody (Middle Region)

Catalog No. ABIN2784968

This Rabbit Polyclonal antibody specifically detects ASB17 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig.

Quick Overview for ASB17 antibody (Middle Region) (ABIN2784968)

Target: ASB17 (Ankyrin Repeat and SOCS Box Containing 17 (ASB17))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB17 Antibody

Binding Specificity: Middle Region

Purpose: ASB17 Antibody - middle region

Sequence: SPLSGITPLF YVAQTRQSNI FKILLQYGIL EREKNPINIV LTIVLYPSRV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ASB17. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB17

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52529-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB17

Target: ASB17 (Ankyrin Repeat and SOCS Box Containing 17 (ASB17))

Alternative Name: ASB17

Background:

Background Information: ASB17 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene Name: Ankyrin repeat and SOCS box containing 17

Alternative Symbols: Asb-17

Protein Name: Ankyrin repeat and SOCS box protein 17

Molecular Weight: 34kDa

Gene ID: 127247

NCBI Accession: NP_543144

UniProt: Q8WXJ9