DEDD2 antibody (Middle Region)

Catalog No. ABIN2784985

Product Details anti-DEDD2 Antibody

Target: DEDD2 (Death Effector Domain Containing 2 (DEDD2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEDD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PQQQSEPARP SSEGKVTCDI RLRVRAEYCE HGPALEQGVA SRRPQALARQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DEDD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DEDD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEDD2

Target: DEDD2 (Death Effector Domain Containing 2 (DEDD2))

Alternative Name: DEDD2 (DEDD2 Products)

Synonyms: FLAME-3 antibody, MGC145883 antibody, 2410050E11Rik antibody, DEDD2 antibody, death effector domain containing 2 antibody, death effector domain containing 2 L homeolog antibody, death effector domain-containing DNA binding protein 2 antibody, DEDD2 antibody, dedd2.L antibody, dedd2 antibody, Dedd2 antibody

Background: DEDD2 may play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. DEDD2 may regulate degradation of intermediate filaments during apoptosis. DEDD2 may play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Alias Symbols: FLAME-3
Protein Interaction Partner: CDCA7L, ATG16L1, CDK6, RBFOX2, NR2E3, HNRNPAB, RHOXF2, GTF3C3, DEDD2, DEDD, CFLAR, CASP8, CASP10,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 162989

NCBI Accession: NM_133328, NP_579874

UniProt: Q8WXF8