C6orf150 antibody (Middle Region)

Catalog No. ABIN2785007

This Rabbit Polyclonal antibody specifically detects C6orf150 in WB. It exhibits reactivity toward Human, Cow, Guinea Pig, Horse, Pig and Rabbit.It has been mentioned in 1 publication

Quick Overview for C6orf150 antibody (Middle Region) (ABIN2785007)

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Reactivity: Human, Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C6orf150 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C6orf150 Antibody

Binding Specificity: Middle Region

Purpose: CGAS Antibody - middle region

Sequence: VPKHAKEGNG FQEETWRLSF SHIEKEILNN HGKSKTCCEN KEEKCCRKDC

Predicted Reactivity: Cow: 86%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against C6orf150. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C6orf150

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52607-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-C6orf150 antibody (ABIN2785007)

Schoggins, Wilson, Panis, Murphy, Jones, Bieniasz, Rice: "A diverse range of gene products are effectors of the type I interferon antiviral response." in: Nature, Vol. 472, Issue 7344, pp. 481-5, (2011) (PubMed).

Target Details for C6orf150

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Alternative Name: CGAS

Background:

Gene Name: cyclic GMP-AMP synthase

Alternative Symbols: MB21D1, h-cGAS, C6orf150

Protein Name: cyclic GMP-AMP synthase

Molecular Weight: 59kDa

Gene ID: 115004

NCBI Accession: NP_612450

UniProt: Q8N884

Pathways: Activation of Innate immune Response