CDC42EP5 antibody (Middle Region)

Catalog No. ABIN2785099

The Rabbit Polyclonal anti-CDC42EP5 antibody has been validated for WB. It is suitable to detect CDC42EP5 in samples from Human, Mouse, Cow, Dog and Rat.

Quick Overview for CDC42EP5 antibody (Middle Region) (ABIN2785099)

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Reactivity: Human, Mouse, Cow, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDC42EP5 Antibody

Binding Specificity: Middle Region

Sequence: HVGRGGDAFG DTSFLSRHGG GPPPEPRAPP AGAPRSPPPP AVPQSAAPSP

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CDC42EP5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC42EP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 148 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC42EP5

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Alternative Name: CDC42EP5

Background: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.
Alias Symbols: Borg3, CEP5, MGC21945, MGC71153
Protein Interaction Partner: SEPT7, CDC42, Sept6, Sept2,
Protein Size: 148

Molecular Weight: 15 kDa

Gene ID: 148170

NCBI Accession: NM_145057, NP_659494

UniProt: Q6NZY7

Pathways: Regulation of Actin Filament Polymerization