OMA1 antibody (Middle Region)

Catalog No. ABIN2785108

This Rabbit Polyclonal antibody specifically detects OMA1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio) and has been mentioned in 2+ publications.

Quick Overview for OMA1 antibody (Middle Region) (ABIN2785108)

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OMA1 Antibody

Binding Specificity: Middle Region

Sequence: WAICPRDSLA LLCQWIQSKL QEYMFNRPYS RKLEAEADKI GLLLAAKACA

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Yeast: 83%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against OMA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OMA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-OMA1 antibody (ABIN2785108)

Bohovych, Fernandez, Rahn, Stackley, Bestman, Anandhan, Franco, Claypool, Lewis, Chan, Khalimonchuk: "Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability." in: Scientific reports, Vol. 5, pp. 13989, (2015) (PubMed).

Bohovych, Donaldson, Christianson, Zahayko, Khalimonchuk: "Stress-triggered activation of the metalloprotease Oma1 involves its C-terminal region and is important for mitochondrial stress protection in yeast." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13259-72, (2014) (PubMed).

Target Details for OMA1

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Alternative Name: OMA1

Background: OMA1 is a mitochondrial protease.
Alias Symbols: 2010001O09Rik, DAB1, FLJ33782, MPRP-1, YKR087C, ZMPOMA1
Protein Size: 524

Molecular Weight: 60 kDa

Gene ID: 115209

NCBI Accession: NM_145243, NP_660286

UniProt: Q96E52