WFDC5 antibody (N-Term)

Catalog No. ABIN2785124

Product Details anti-WFDC5 Antibody

Target: WFDC5 (WAP Four-Disulfide Core Domain 5 (WFDC5))

Binding Specificity: N-Term

Reactivity: Human, Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MRTQSLLLLG ALLAVGSQLP AVFGRKKGEK SGGCPPDDGP CLLSVPDQCV

Predicted Reactivity: Cow: 79%, Guinea Pig: 85%, Human: 100%, Pig: 86%

Characteristics: This is a rabbit polyclonal antibody against WFDC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WFDC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 123 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WFDC5

Target: WFDC5 (WAP Four-Disulfide Core Domain 5 (WFDC5))

Alternative Name: WFDC5 (WFDC5 Products)

Synonyms: Prg5 antibody, Wap1 antibody, BC019734 antibody, PRG5 antibody, WAP1 antibody, dJ211D12.5 antibody, WAP four-disulfide core domain 5 antibody, Wfdc5 antibody, WFDC5 antibody

Background: WFDC5 is a putative acid-stable proteinase inhibitor.This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Alias Symbols: PRG5, WAP1, dJ211D12.5
Protein Interaction Partner: PDS5A, PDS5B, STAG2, STAG1, SMC3, SMC1A, RAD21,
Protein Size: 123

Molecular Weight: 11 kDa

Gene ID: 149708

NCBI Accession: NM_145652, NP_663627

UniProt: Q8TCV5