WAP Four-Disulfide Core Domain 5 (WFDC5) (N-Term) antibody

Details for Product No. ABIN2785124, Supplier: Log in to see
Antigen
  • Prg5
  • Wap1
  • BC019734
  • PRG5
  • WAP1
  • dJ211D12.5
  • WAP four-disulfide core domain 5
  • Wfdc5
  • WFDC5
Epitope
N-Term
6
5
3
2
1
1
1
Reactivity
Cow (Bovine), Guinea Pig, Human, Pig (Porcine)
43
8
3
1
1
1
Host
Rabbit
30
24
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
37
27
21
13
6
4
3
2
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human WFDC5
Blocking Peptide Blocking peptide for this product available: ABIN986195
Sequence MRTQSLLLLG ALLAVGSQLP AVFGRKKGEK SGGCPPDDGP CLLSVPDQCV
Predicted Reactivity Cow: 79%, Guinea Pig: 85%, Human: 100%, Pig: 86%
Characteristics This is a rabbit polyclonal antibody against WFDC5. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Antigen
Alternative Name WFDC5 (WFDC5 Antibody Abstract)
Background WFDC5 is a putative acid-stable proteinase inhibitor.This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Alias Symbols: PRG5, WAP1, dJ211D12.5
Protein Interaction Partner: PDS5A, PDS5B, STAG2, STAG1, SMC3, SMC1A, RAD21,
Protein Size: 123
Molecular Weight 11 kDa
Gene ID 149708
NCBI Accession NM_145652, NP_663627
UniProt Q8TCV5
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 123 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-WAP Four-Disulfide Core Domain 5 (WFDC5) (N-Term) antibody (ABIN2785124) WB Suggested Anti-WFDC5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Mukhopadhyay, Rosen: "The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells." in: Biochemical and biophysical research communications, Vol. 358, Issue 3, pp. 770-6, 2007 (PubMed).

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