FBXO32 antibody (C-Term)

Catalog No. ABIN2785131

This Rabbit Polyclonal antibody specifically detects FBXO32 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for FBXO32 antibody (C-Term) (ABIN2785131)

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO32 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO32 Antibody

Binding Specificity: C-Term

Sequence: LVRCYPRREQ YGVTLQLCKH CHILSWKGTD HPCTANNPES CSVSLSPQDF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Fbxo32. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region from the human protein.

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Alternative Name: Fbxo32

Background: Fbxo32 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy.
Alias Symbols: 4833442G10Rik, AI430017, ATROGIN1, MAFbx, atrogin-1, Gm20361
Protein Interaction Partner: Nfkbia, Myod1, Telo2, 9130011E15Rik, Prdm16, Ube2v2, Taf15, Inf2, Sync, Rps13, Tubb6, Fbxo32, Rplp2, Eef1g, Rpl14, Cand2, Srp72, Ube2v1, Ahnak, Eif3f, Atp5d, Srsf4, Adrm1, Mettl3, Pgam2, Eef1b2, Ubqln2, Ywhab, Clpp, Hnrnpa2b1, Mybph, Thop1, Eif3b, Cul1, C
Protein Size: 355

Molecular Weight: 39 kDa

Gene ID: 67731

NCBI Accession: NM_026346, NP_080622

UniProt: Q9CPU7