OST alpha antibody (Middle Region)

Catalog No. ABIN2785228

This Rabbit Polyclonal antibody specifically detects OST alpha in WB. It exhibits reactivity toward Human, Cow, Horse, Dog, Guinea Pig, Mouse, Rabbit and Rat.

Quick Overview for OST alpha antibody (Middle Region) (ABIN2785228)

Target: OST alpha (OSTALPHA) (Organic Solute Transporter alpha (OSTALPHA))

Reactivity: Human, Cow, Horse, Dog, Guinea Pig, Mouse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OST alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OST alpha Antibody

Binding Specificity: Middle Region

Purpose: OSTalpha Antibody - middle region

Sequence: LLMLGPFQYA FLKITLTLVG LFLVPDGIYD PADISEGSTA LWINTFLGVS

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against OSTalpha. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OSTalpha

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53102-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for OST alpha

Target: OST alpha (OSTALPHA) (Organic Solute Transporter alpha (OSTALPHA))

Alternative Name: OSTalpha

Background:

Targeted Subunit: alpha

Background Information: OSTalpha is essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood.OSTalpha efficiently transports the major species of bile acids.

Gene Name: Organic solute transporter alpha

Alternative Symbols: OSTA, OSTalpha

Protein Name: Organic solute transporter subunit alpha

Molecular Weight: 38 kDa

Gene ID: 200931

NCBI Accession: NP_689885

UniProt: Q86UW1