FBXL16 antibody (Middle Region)

Catalog No. ABIN2785266

This Rabbit Polyclonal antibody specifically detects FBXL16 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for FBXL16 antibody (Middle Region) (ABIN2785266)

Target: FBXL16 (F-Box and Leucine-Rich Repeat Protein 16 (FBXL16))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL16 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXL16 Antibody

Binding Specificity: Middle Region

Purpose: FBXL16 Antibody - middle region

Sequence: GCPLLTTTGL SGLVQLQELE ELELTNCPGA TPELFKYFSQ HLPRCLVIE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FBXL16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXL16

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53165-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXL16

Target: FBXL16 (F-Box and Leucine-Rich Repeat Protein 16 (FBXL16))

Alternative Name: FBXL16

Background:

Background Information: FBXL16 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Gene Name: F-box and leucine-rich repeat protein 16

Alternative Symbols: Fbl16, C16orf22, c380A1.1

Protein Name: F-box/LRR-repeat protein 16

Molecular Weight: 52kDa

Gene ID: 146330

NCBI Accession: NP_699181

UniProt: Q8N461