SH2D3C antibody (N-Term)

Catalog No. ABIN2785290

This Rabbit Polyclonal antibody specifically detects SH2D3C in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio) and Horse.

Quick Overview for SH2D3C antibody (N-Term) (ABIN2785290)

Target: SH2D3C (SH2 Domain Containing 3C (SH2D3C))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D3C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SH2D3C Antibody

Binding Specificity: N-Term

Sequence: AGSDYVKFSK EKYILDSSPE KLHKELEEEL KLSSTDLRSH AWYHGRIPRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SH2D3C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SH2D3C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 703 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH2D3C

Target: SH2D3C (SH2 Domain Containing 3C (SH2D3C))

Alternative Name: SH2D3C

Background: SH2D3C is an Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 of SH2D3C is required to induce membrane ruffling and promote EGF-dependent cell migration.
Alias Symbols: CHAT, FLJ39664, NSP3, PRO34088
Protein Interaction Partner: LYN, NEDD9, EFS, CARD11, SNCAIP, BCAR1, PTK2B, EPHB2, SRC, MAPK1,
Protein Size: 703

Molecular Weight: 77 kDa

Gene ID: 10044

NCBI Accession: NM_170600, NP_733745