FUNDC1 antibody (N-Term)

Catalog No. ABIN2785323

Cited in 2+ publications. The Rabbit Polyclonal anti-FUNDC1 antibody (ABIN2785323) specifically detects FUNDC1 in WB and IP. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for FUNDC1 antibody (N-Term) (ABIN2785323)

Target: FUNDC1 (FUN14 Domain Containing 1 (FUNDC1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUNDC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FUNDC1 Antibody

Binding Specificity: N-Term

Purpose: FUNDC1 Antibody - N-terminal region

Sequence: MATRNPPPQD YESDDDSYEV LDLTEYARRH QWWNRVFGHS SGPMVEKYSV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FUNDC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FUNDC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53280-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-FUNDC1 antibody (ABIN2785323)

Zhang, Yin, Zhang, Qi, Ma, Gao, Wang, Jing: "Spermidine preconditioning ameliorates laurate-induced brain injury by maintaining mitochondrial stability." in: Neurological research, Vol. 39, Issue 3, pp. 248-258, (2017) (PubMed).

Huang, Sivagurunathan, Ting, Jansson, Austin, Kelly, Semsarian, Zhang, Richardson: "Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2? phosphorylation, and the induction of downstream targets." in: The American journal of pathology, Vol. 183, Issue 3, pp. 745-57, (2013) (PubMed).

Target Details for FUNDC1

Target: FUNDC1 (FUN14 Domain Containing 1 (FUNDC1))

Alternative Name: FUNDC1

Background:

Background Information: FUNDC1 belongs to the FUN14 family. The exact function of FUNDC1 remains unknown.

Gene Name: FUN14 domain containing 1

Alternative Symbols: MGC51029

Protein Name: FUN14 domain-containing protein 1

Molecular Weight: 17 kDa

Gene ID: 139341

NCBI Accession: NP_776155

UniProt: Q8IVP5