Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding two different isoforms were identified through sequence analysis.
Alias Symbols: AAVG5835, DKFZp686D1387, L55nt, MGC61802, MRP-L55, PRO19675
Protein Interaction Partner: MRPL52, MRPL9, MRPL32, MRPL41, MRPS9, MRPL39, MRPL51, MRPL15, MRPL13, MRPL3, TOMM40, FLOT1, RPS23, MRPL23, HNRNPM, ILF3, ILF2, ICT1,
Protein Size: 128