ARHGEF25/GEFT antibody (C-Term)

Catalog No. ABIN2785393

The Rabbit Polyclonal anti-ARHGEF25/GEFT antibody (ABIN2785393) specifically detects ARHGEF25/GEFT in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit samples.

Quick Overview for ARHGEF25/GEFT antibody (C-Term) (ABIN2785393)

Target: ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF25/GEFT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARHGEF25/GEFT Antibody

Binding Specificity: C-Term

Purpose: GEFT Antibody - C-terminal region

Sequence: RLGDQAQGST HTPINGSLPS LLLSPKGEVA RALLPLDKQA LGDIPQAPHD

Predicted Reactivity: Cow: 92%, Dog: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 85%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against GEFT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GEFT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53438-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARHGEF25/GEFT

Target: ARHGEF25/GEFT (ARHGEF25) (Rho Guanine Nucleotide Exchange Factor 25 (ARHGEF25))

Alternative Name: GEFT

Background:

Background Information: The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).[supplied by OMIM].

Gene Name: Rho guanine nucleotide exchange factor (GEF) 25

Alternative Symbols: GEFT, p63RhoGEF

Protein Name: Rho guanine nucleotide exchange factor 25

Molecular Weight: 64kDa

Gene ID: 115557

NCBI Accession: NP_891992

UniProt: Q86VW2