PHACTR3 antibody (C-Term)

Catalog No. ABIN2785398

Product Details anti-PHACTR3 Antibody

Target: PHACTR3 (Phosphatase and Actin Regulator 3 (PHACTR3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHACTR3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IEMKLSKRLS QRPAVEELER RNILKQRNDQ TEQEERREIK QRLTRKLNQR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PHACTR3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHACTR3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 448 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHACTR3

Target: PHACTR3 (Phosphatase and Actin Regulator 3 (PHACTR3))

Alternative Name: PHACTR3 (PHACTR3 Products)

Synonyms: C20orf101 antibody, H17739 antibody, SCAPIN1 antibody, SCAPININ antibody, 1500003N10Rik antibody, 4930415A02Rik antibody, Scapin1 antibody, Scapinin antibody, mKIAA4224 antibody, scapinin antibody, h17739 antibody, scapin1 antibody, DKFZp459A1919 antibody, zgc:109967 antibody, zgc:172129 antibody, phosphatase and actin regulator 3 antibody, phosphatase and actin regulator 3 L homeolog antibody, phosphatase and actin regulator 3b antibody, phosphatase and actin regulator 3a antibody, PHACTR3 antibody, Phactr3 antibody, phactr3.L antibody, phactr3 antibody, LOC100543179 antibody, phactr3b antibody, phactr3a antibody

Background: PHACTR3 is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1.The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.
Alias Symbols: C20orf101, H17739, MGC117178, SCAPIN1, SCAPININ
Protein Interaction Partner: PPP1CA, TAB1, MAPK6, EEF1G,
Protein Size: 448

Molecular Weight: 51 kDa

Gene ID: 116154

NCBI Accession: NM_183246, NP_899069

UniProt: B1AN69