DNALI1 antibody (N-Term)

Catalog No. ABIN2785474

Product Details anti-DNALI1 Antibody

Target: DNALI1 (Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNALI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MVTANKAHTG QGSCWVATLA SAMIPPADSL LKYDTPVLVS RNTEKRSPKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DNALI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNALI1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 280 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNALI1

Target: DNALI1 (Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1))

Alternative Name: DNALI1 (DNALI1 Products)

Synonyms: zgc:171493 antibody, zgc:171595 antibody, P28 antibody, dJ423B22.5 antibody, hp28 antibody, 1700023A09Rik antibody, AW049135 antibody, dynein axonemal light intermediate chain 1 antibody, dynein, axonemal, light intermediate chain 1 antibody, dynein axonemal light intermediate chain 1 S homeolog antibody, dynein, axonemal, light intermediate polypeptide 1 antibody, DNALI1 antibody, dnali1 antibody, dnali1.S antibody, Dnali1 antibody

Background: DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Alias Symbols: P28, dJ423B22.5, hp28
Protein Interaction Partner: SIAH1, PRMT6, APP, DNALI1, HTT, ABCF3, EPS8,
Protein Size: 280

Molecular Weight: 31 kDa

Gene ID: 7802

NCBI Accession: NM_003462, NP_003453

UniProt: O14645