DNALI1 antibody (N-Term)

Catalog No. ABIN2785474

The Rabbit Polyclonal anti-DNALI1 antibody is suitable to detect DNALI1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB and IHC.

Quick Overview for DNALI1 antibody (N-Term) (ABIN2785474)

Target: DNALI1 (Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNALI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DNALI1 Antibody

Binding Specificity: N-Term

Purpose: DNALI1 Antibody - N-terminal region

Sequence: MVTANKAHTG QGSCWVATLA SAMIPPADSL LKYDTPVLVS RNTEKRSPKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DNALI1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNALI1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53611-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNALI1

Target: DNALI1 (Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1))

Alternative Name: DNALI1

Background:

Background Information: DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.

Gene Name: Dynein, axonemal, light intermediate chain 1

Alternative Symbols: P28, hp28, dJ423B22.5

Protein Name: Axonemal dynein light intermediate polypeptide 1

Molecular Weight: 31kDa

Gene ID: 7802

NCBI Accession: NP_003453

UniProt: O14645