PDXK antibody (N-Term)

Catalog No. ABIN2785476

The Rabbit Polyclonal anti-PDXK antibody is suitable to detect PDXK in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse and Sheep. It has been validated for WB and IHC.

Quick Overview for PDXK antibody (N-Term) (ABIN2785476)

Target: PDXK (Pyridoxal Kinase (PDXK))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDXK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PDXK Antibody

Binding Specificity: N-Term

Purpose: PDXK Antibody - N-terminal region

Sequence: PLQVLGFEID AVNSVQFSNH TGYAHWKGQV LNSDELQELY EGLRLNNMNK

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 92%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against PDXK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDXK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53615-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDXK

Target: PDXK (Pyridoxal Kinase (PDXK))

Alternative Name: PDXK

Background:

Background Information: PDXK phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. PDXK is cytoplasmic and probably acts as a homodimer. The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Pyridoxal (pyridoxine, vitamin B6) kinase

Alternative Symbols: PKH, PNK, HMSN6C, PRED79, C21orf97, HEL-S-1a, C21orf124

Protein Name: Pyridoxal kinase

Molecular Weight: 34kDa

Gene ID: 8566

NCBI Accession: NP_003672

UniProt: O00764