PDE1A antibody (C-Term)

Catalog No. ABIN2785487

The Rabbit Polyclonal anti-PDE1A antibody has been validated for WB. It is suitable to detect PDE1A in samples from Human, Mouse, Rat and Dog.

Quick Overview for PDE1A antibody (C-Term) (ABIN2785487)

Target: PDE1A (Phosphodiesterase 1A (PDE1A))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE1A Antibody

Binding Specificity: C-Term

Sequence: AVDLKSFKNN LVDIIQQNKE RWKELAAQGE SDLHKNSEDL VNAEEKHDET

Predicted Reactivity: Dog: 93%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PDE1A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PDE1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 545 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE1A

Target: PDE1A (Phosphodiesterase 1A (PDE1A))

Alternative Name: PDE1A

Background: PDE1A belongs to the cyclic nucleotide phosphodiesterase family. It has a higher affinity for cGMP than for cAMP. The exact function of PDE1A remains unknown.
Alias Symbols: HCAM1, HSPDE1A, MGC26303
Protein Interaction Partner: UBC, APP, APOA1, CALM1,
Protein Size: 545

Molecular Weight: 60 kDa

Gene ID: 5136

NCBI Accession: NM_005019, NP_005010

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma