TUBA3C antibody (Tubulin, Alpha, 3C) (N-Term)

Details for Product anti-TUBA3C Antibody No. ABIN2785497, Supplier: Log in to see
Antigen
  • TUBA3C
  • TUBA3D
  • TUBA2
  • bA408E5.3
  • TUBA1A
  • TUBA3
  • TUBA4A
  • tubulin alpha-1A chain
  • tubulin alpha 3c
  • tubulin alpha-1B chain
  • tubulin alpha like 3
  • LOC782966
  • TUBA3C
  • LOC610636
  • TUBAL3
Alternatives
anti-Caenorhabditis elegans (C. elegans) TUBA3C antibody for Western Blotting
Epitope
N-Term
12
12
8
5
3
2
2
2
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
39
5
5
3
3
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
29
10
Clonality
Polyclonal
Conjugate
This TUBA3C antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
38
26
6
4
4
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TUBA3C
Blocking Peptide Blocking peptide for this product available: ABIN985732
Sequence QMPSDKTIGG GDDSFNTFFS ETGAGKHVPR AVFVDLEPTV VDEVRTGTYR
Predicted Reactivity Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against TUBA3C. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TUBA3C (TUBA3C Antibody Abstract)
Background Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99 % identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TUBA2, bA408E5.3, TUBA3D
Protein Interaction Partner: CEP70, UBC, MDM2, CD81, K3, UBL4A, DYNLT1, TSGA10, CUL3, ARRB2, ARRB1, VHL, YWHAQ, DYRK2, YWHAZ, YWHAG, YWHAB, PPP4C, PFDN5, GRM7, NMI, PXN, SIAH1, DYNLL1, TUBG1, MYC, FYN, FBL,
Protein Size: 450
Molecular Weight 50 kDa
Gene ID 7278
NCBI Accession NM_006001, NP_005992
UniProt Q13748
Pathways Microtubule Dynamics
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 450 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Tubulin, Alpha, 3C (TUBA3C) (N-Term) antibody (ABIN2785497) WB Suggested Anti-TUBA3C Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Jin, Smith, Stark, Wells, Fawcett, Kulkarni, Metalnikov, ODonnell, Taylor, Taylor, Zougman, Woodgett, Langeberg, Scott, Pawson: "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization." in: Current biology : CB, Vol. 14, Issue 16, pp. 1436-50, 2004 (PubMed).

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