FEM1B antibody (Middle Region)

Catalog No. ABIN2785526

This anti-FEM1B antibody is a Rabbit Polyclonal antibody detecting FEM1B in WB. Suitable for Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for FEM1B antibody (Middle Region) (ABIN2785526)

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEM1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FEM1B Antibody

Binding Specificity: Middle Region

Sequence: FQDGDNILEK EVLPPIHAYG NRTECRNPQE LESIRQDRDA LHMEGLIVRE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FEM1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FEM1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 627 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FEM1B

Target: FEM1B (Fem-1 Homolog B (FEM1B))

Alternative Name: FEM1B

Background: FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. FEM1B also involved in glucose homeostasis in pancreatic islet.
Alias Symbols: DKFZp451E0710, FIAA, F1A-ALPHA
Protein Interaction Partner: GLI1, HIF1AN, NKX3-1, fem-2, Ppm1f, UBC, RBX1, CUL2, TCEB2, TCEB1, Tnfrsf1a, Fem1b, Fas, Casp3, COPS4, RAD9A, CHEK1, DCUN1D1, COPS5, COPS6, CUL5, NEDD8, KIAA0319, GNB2L1, APAF1,
Protein Size: 627

Molecular Weight: 69 kDa

Gene ID: 10116

NCBI Accession: NM_015322, NP_056137

UniProt: Q9UK73