Ubiquilin 3 antibody (N-Term)

Catalog No. ABIN2785537

The Rabbit Polyclonal anti-Ubiquilin 3 antibody (ABIN2785537) specifically detects Ubiquilin 3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Horse, Pig, Rabbit and Dog samples.

Quick Overview for Ubiquilin 3 antibody (N-Term) (ABIN2785537)

Target: Ubiquilin 3 (UBQLN3)

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ubiquilin 3 Antibody

Binding Specificity: N-Term

Purpose: UBQLN3 Antibody - N-terminal region

Sequence: LMRQHVSVPE FVTQLIDDPF IPGLLSNTGL VRQLVLDNPH MQQLIQHNPE

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against UBQLN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBQLN3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53722-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Ubiquilin 3

Target: Ubiquilin 3 (UBQLN3)

Alternative Name: UBQLN3

Background:

Background Information: UBQLN3 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. UBQLN3 is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis. This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.

Gene Name: Ubiquilin 3

Alternative Symbols: TUP-1

Protein Name: Ubiquilin-3

Molecular Weight: 72kDa

Gene ID: 50613

NCBI Accession: NP_059509

UniProt: Q9H347