TTC12 antibody (C-Term)

Catalog No. ABIN2785539

The Rabbit Polyclonal anti-TTC12 antibody is suitable to detect TTC12 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for TTC12 antibody (C-Term) (ABIN2785539)

Target: TTC12 (Tetratricopeptide Repeat Domain 12 (TTC12))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TTC12 Antibody

Binding Specificity: C-Term

Purpose: TTC12 Antibody - C-terminal region

Sequence: MNLCLQAPFV SEVWAVEVSR RCLSLLNSQD GGILTRAAGV LSRTLSSSLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TTC12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TTC12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113709

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTC12

Target: TTC12 (Tetratricopeptide Repeat Domain 12 (TTC12))

Alternative Name: TTC12

Background:

Background Information: TTC12 contains 3 TPR repeats. Hypermethylation of TTC12 gene may play a role in acute lymphoblastic leukemia. Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.

Gene Name: Tetratricopeptide repeat domain 12

Alternative Symbols: TPARM, CILD45

Protein Name: Tetratricopeptide repeat domain 12, isoform CRA_a EMBL EAW67210.1

Molecular Weight: 81kDa

Gene ID: 54970

NCBI Accession: NP_060338

UniProt: B0YJB4