EDDM3B antibody (Middle Region)

Catalog No. ABIN2785559

The Rabbit Polyclonal anti-EDDM3B antibody (ABIN2785559) specifically detects EDDM3B in WB. The antibody is reactive with Human samples.

Quick Overview for EDDM3B antibody (Middle Region) (ABIN2785559)

Target: EDDM3B (Epididymal Protein 3B (EDDM3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDDM3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EDDM3B Antibody

Binding Specificity: Middle Region

Purpose: EDDM3B Antibody - middle region

Sequence: ISWYKIEHIC TSDNWMDRFR NAYVWVQNPL KVLKCHQENS KNSYTESRSF

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against EDDM3B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53756-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EDDM3B

Target: EDDM3B (Epididymal Protein 3B (EDDM3B))

Alternative Name: EDDM3B

Background:

Background Information: Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.

Gene Name: Epididymal protein 3B

Alternative Symbols: EP3B, HE3B, RAM2, FAM12B, HE3-BETA

Protein Name: Epididymal secretory protein E3-beta

Molecular Weight: 16kDa

Gene ID: 64184

NCBI Accession: NP_071755

UniProt: P56851