PAOX antibody (C-Term)

Catalog No. ABIN2785601

The Rabbit Polyclonal anti-PAOX antibody (ABIN2785601) specifically detects PAOX in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Cow, Rabbit, Guinea Pig and Dog samples.

Quick Overview for PAOX antibody (C-Term) (ABIN2785601)

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Reactivity: Human, Mouse, Rat, Horse, Cow, Rabbit, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAOX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAOX Antibody

Binding Specificity: C-Term

Sequence: LCLTQVLRRV TGNPRLPAPK SVLRSRWHSA PYTRGSYSYV AVGSTGGDLD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PAOX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PAOX

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 232 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAOX

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Alternative Name: PAOX

Background: PAOX belongs to the flavin monoamine oxidase family. PAOX is a flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N(1)-acetylspermidine to putrescine. PAOX does not oxidize spermidine. It plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Alias Symbols: RP11-122K13.11, DKFZp434J245, MGC45464, PAO
Protein Interaction Partner: PEX5,
Protein Size: 232

Molecular Weight: 25 kDa

Gene ID: 196743

UniProt: Q6QHF9