MAGEA4 antibody (C-Term)

Catalog No. ABIN2785699

Product Details anti-MAGEA4 Antibody

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ENYLEYRQVP GSNPARYEFL WGPRALAETS YVKVLEHVVR VNARVRIAYP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MAGEA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MAGEA4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 317 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA4

Target: MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))

Alternative Name: MAGEA4 (MAGEA4 Products)

Background: MAGEA4 is a member of the MAGEA family. The members of this family are proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
Alias Symbols: MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336, CT1.4
Protein Interaction Partner: AMOTL2, WBP2, UQCRB, TK1, GTF3C1, TEKT4, TRIM69, TIGD5, BEX2, UBXN6, AMOT, ARNT2, UBC, APP, HLA-A, PIAS2, PSMD10, POT1,
Protein Size: 317

Molecular Weight: 35 kDa

Gene ID: 4103

NCBI Accession: NM_001011548, NP_001011548

UniProt: P43358