ICT1 antibody (Middle Region)

Catalog No. ABIN2785783

This Rabbit Polyclonal antibody specifically detects ICT1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog and Horse.

Quick Overview for ICT1 antibody (Middle Region) (ABIN2785783)

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ICT1 Antibody

Binding Specificity: Middle Region

Sequence: AEWIAEPVRQ KIAITHKNKI NRLGELILTS ESSRYQFRNL ADCLQKIRDM

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ICT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ICT1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ICT1

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Alternative Name: ICT1

Background: The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.
Alias Symbols: DS-1, DS1
Protein Interaction Partner: UBC, LIN28A, MRPS6, MRPS27, DAP3, MRPS18B, MRPL3, MRPL12, NPM1, MTHFD1, SYNCRIP, FLOT1, PPT2, RPL14, EIF4H, UQCRFS1, SRSF3, RPS18, RPS15, MRPL23, RPL4, RPL3, NDUFB7, NDUFB5, NDUFA2, ILF2, HNRNPU, CYC1, CLPTM1, CDH2, CALU, APP, ERGIC1, DDX28, SYNJ2BP, MRPL
Protein Size: 206

Molecular Weight: 23 kDa

Gene ID: 3396

NCBI Accession: NM_001545, NP_001536

UniProt: Q14197