LUM antibody (Middle Region)

Catalog No. ABIN2785836

This Rabbit Polyclonal antibody specifically detects LUM in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit and Pig.

Quick Overview for LUM antibody (Middle Region) (ABIN2785836)

Target: LUM (Lumican (LUM))

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LUM Antibody

Binding Specificity: Middle Region

Purpose: LUM Antibody - middle region

Sequence: AFKGLKSLEY LDLSFNQIAR LPSGLPVSLL TLYLDNNKIS NIPDEYFKRF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against LUM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LUM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54695-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: LUM

Background:

Background Information: This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Gene Name: Lumican

Alternative Symbols: LDC, SLRR2D

Protein Name: Lumican

Molecular Weight: 37kDa

Gene ID: 4060

NCBI Accession: NP_002336

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process