EPS8 antibody (C-Term)

Catalog No. ABIN2785853

This Rabbit Polyclonal antibody specifically detects EPS8 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for EPS8 antibody (C-Term) (ABIN2785853)

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPS8 Antibody

Binding Specificity: C-Term

Purpose: EPS8 Antibody - C-terminal region

Sequence: VFNQITVQKA ALEDSNGSSE LQEIMRRRQE KISAAASDSG VESFDEGSSH

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Eps8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of mouse EPS8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54727-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPS8

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Alternative Name: EPS8

Background:

Background Information: This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene Name: epidermal growth factor receptor pathway substrate 8

Alternative Symbols: DFNB102

Protein Name: epidermal growth factor receptor kinase substrate 8

Molecular Weight: 61kDa

Gene ID: 2059

NCBI Accession: NP_004438

UniProt: Q12929

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization