TIMM13 antibody (N-Term)
Quick Overview for TIMM13 antibody (N-Term) (ABIN2785946)
Target
See all TIMM13 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- N-Term
-
Sequence
- FGSDFGGTGG GKLDPGAIME QVKVQIAVAN AQELLQRMTD KCFRKCIGKP
-
Predicted Reactivity
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
-
Characteristics
- This is a rabbit polyclonal antibody against Timm13. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
-
-
-
-
Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
-
Comment
-
Antigen size: 95 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- TIMM13 (Translocase of Inner Mitochondrial Membrane 13 Homolog (TIMM13))
-
Alternative Name
- Timm13
-
Background
-
Timm13 is a mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. It is also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. It acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
Alias Symbols: D10Ertd378e, Tim9, Timm9
Protein Size: 95 -
Molecular Weight
- 10 kDa
-
Gene ID
- 30055
-
NCBI Accession
- NM_013895, NP_038923
-
UniProt
- P62075
-
Pathways
- Sensory Perception of Sound
Target
-