TXN2 antibody (Middle Region)

Catalog No. ABIN2785948

Product Details anti-TXN2 Antibody

Target: TXN2 (Thioredoxin 2 (TXN2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VDIDDHTDLA IEYEVSAVPT VLAMKNGDVV DKFVGIKDED QLEAFLKKLI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against TXN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TXN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 166 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TXN2

Target: TXN2 (Thioredoxin 2 (TXN2))

Alternative Name: TXN2 (TXN2 Products)

Background: TXN2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. TXN2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MT-TRX, MTRX, TRX2
Protein Interaction Partner: TRIM21, VPS52, FAM9B, RBM45, KRT40, MRFAP1L1, CCDC114, REEP6, TIFA, PPCDC, SCYL3, AGTRAP, RABGEF1, MTUS2, RPIA, MAPRE3, MAPRE2, STUB1, PSME3, SSNA1, ZBTB14, TRIP6, RELA, MAGEA11, NR3C1, DCTD, AP2B1, GPRASP2, SHARPIN, THAP1, RABAC1, VIM, MLH1, KRT18, ALDOB
Protein Size: 166

Molecular Weight: 12 kDa

Gene ID: 25828

NCBI Accession: NM_012473, NP_036605

UniProt: Q99757

Pathways: Cell RedoxHomeostasis