TXN2 antibody (Middle Region)

Catalog No. ABIN2785948

The Rabbit Polyclonal anti-TXN2 antibody is suitable to detect TXN2 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for TXN2 antibody (Middle Region) (ABIN2785948)

Target: TXN2 (Thioredoxin 2 (TXN2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TXN2 Antibody

Binding Specificity: Middle Region

Purpose: TXN2 Antibody - middle region

Sequence: VDIDDHTDLA IEYEVSAVPT VLAMKNGDVV DKFVGIKDED QLEAFLKKLI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against TXN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TXN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54910-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TXN2

Target: TXN2 (Thioredoxin 2 (TXN2))

Alternative Name: TXN2

Background:

Background Information: TXN2 is a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. TXN2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Thioredoxin 2

Alternative Symbols: TXN, MTRX, TRX2, MT-TRX, COXPD29

Protein Name: Thioredoxin, mitochondrial

Molecular Weight: 12kDa

Gene ID: 25828

NCBI Accession: NP_036605

UniProt: Q99757

Pathways: Cell RedoxHomeostasis