Epsin 1 antibody (C-Term)

Catalog No. ABIN2785964

This Rabbit Polyclonal antibody specifically detects Epsin 1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow, Dog and Horse.

Quick Overview for Epsin 1 antibody (C-Term) (ABIN2785964)

Target: Epsin 1 (EPN1)

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epsin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Epsin 1 Antibody

Binding Specificity: C-Term

Purpose: EPN1 Antibody - C-terminal region

Sequence: AATPTPTPPT RKTPESFLGP NAALVDLDSL VSRPGPTPPG AKASNPFLPG

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against EPN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EPN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54939-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Epsin 1

Target: Epsin 1 (EPN1)

Alternative Name: EPN1

Background:

Background Information: EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1, MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of clathrin-coated vesicles.EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1, MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of clathrin-coated vesicles.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-19 AK022454.1 1-19 20-2430 BC044651.1 1-2411

Gene Name: Epsin 1

Alternative Symbols: -

Protein Name: Epsin-1

Molecular Weight: 57kDa

Gene ID: 29924

NCBI Accession: NP_037465

UniProt: Q9Y6I3

Pathways: EGFR Signaling Pathway, EGFR Downregulation