PES1 antibody (C-Term)

Catalog No. ABIN2786001

The Rabbit Polyclonal anti-PES1 antibody is suitable to detect PES1 in samples from Human, Mouse, Rat, Cow, Pig, Horse, Rabbit, Dog, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for PES1 antibody (C-Term) (ABIN2786001)

Target: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Reactivity: Human, Mouse, Rat, Cow, Pig, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PES1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PES1 Antibody

Binding Specificity: C-Term

Purpose: PES1 Antibody - C-terminal region

Sequence: KKREKYLYQK IMFGKRRKIR EANKLAEKRK AHDEAVRSEK KAKKARPE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PES1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PES1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55008-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PES1

Target: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Alternative Name: PES1

Background:

Background Information: PES1 is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression.This gene encodes a protein that is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Pescadillo ribosomal biogenesis factor 1

Alternative Symbols: PES, NOP7

Protein Name: Pescadillo homolog

Molecular Weight: 68kDa

Gene ID: 23481

NCBI Accession: NP_055118

UniProt: O00541